| Bioactivity | Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline also inhibits the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) with IC50s between 5 μM and 50 μM for differing isoforms. Paxilline possesses significant anticonvulsant activity[1][2][3]. | ||||||||||||
| Name | Paxilline | ||||||||||||
| CAS | 57186-25-1 | ||||||||||||
| Formula | C27H33NO4 | ||||||||||||
| Molar Mass | 435.56 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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