| Bioactivity | PX20606 trans racemate (PX-102 trans racemate) is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively[1]. | ||||||||||||
| Target | EC50: 32 nM (FXR in FRET assay), 34 nM (FXR in M1H assay) | ||||||||||||
| Name | PX20606 trans racemate | ||||||||||||
| CAS | 1268244-85-4 | ||||||||||||
| Formula | C29H22Cl3NO4 | ||||||||||||
| Molar Mass | 554.85 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Kinzel O, et al. Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3746-53. |
PX20606 trans racemate
CAS: 1268244-85-4 F: C29H22Cl3NO4 W: 554.85
PX20606 trans racemate (PX-102 trans racemate) is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay
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