Bioactivity | PTP1B-IN-26 (Compound 7a) is a derivative of phenylthiosemicarbazide‐phenoxy‐1,2,3‐triazole‐N‐phenylacetamide. PTP1B-IN-26 is an inhibitor of protein tyrosine phosphatase 1B (PTP-1B). PTP1B-IN-26 is a competitive inhibitor. PTP1B-IN-26 can be used to research in type 2 diabetes. |
Formula | C25H23N7O2S |
Molar Mass | 485.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ansariashlaghi S, Fakhrioliaei A, Mohammadi‐Khanaposhtani M, et al. New phenylthiosemicarbazide‐phenoxy‐1, 2, 3‐triazole‐N‐phenylacetamides as dual inhibitors against α‐glucosidase and PTP‐1B for the treatment of type 2 diabetes[J]. Archiv der Pharmazie, 2024: e2300517. |