| Bioactivity | PROTAC Vif degrader-1 (Compound L15) is a Vif PROTAC degrader. PROTAC Vif degrader-1 has antiviral activity against HIV-1 (EC50: 33.35 μM against HIV-1IIIB). Blue: CRBN ligand (HY-10984); Black: linker; Pink: HIV-1 inhibitor(HY-163852)[1]. |
| Invitro | PROTAC Vif degrader-1 可抑制 PBMCs 中不同野生型 HIV-1 菌株的复制 （对于 HIV-1kiz002 和 HIV-1WAN EC50 分别为 10.53 μM 和 8.76 μM)，且细胞毒性较低 (CC50: > 200 µM)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PROTAC Vif degrader-1 相关抗体: |
| Formula | C41H41N7O12S |
| Molar Mass | 855.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Luo D, et al. Discovery of L15 as a novel Vif PROTAC degrader with antiviral activity against HIV-1. Bioorg Med Chem Lett. 2024 Jul 10;111:129880. |
PROTAC Vif degrader-1
CAS: F: C41H41N7O12S W: 855.87
PROTAC Vif degrader-1 (Compound L15) is a Vif PROTAC degrader. PROTAC Vif degrader-1 has antiviral activity against HIV-
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.