| Bioactivity | PROTAC SMARCA2/4-degrader-33 (compound I-277) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC50s 90 after 24 h of treatment[1]. |
| Target | SMARCA2/4 |
| CAS | 2568276-36-6 |
| Formula | C44H51N11O4 |
| Molar Mass | 797.95 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17. |
PROTAC SMARCA2/4-degrader-33
CAS: 2568276-36-6 F: C44H51N11O4 W: 797.95
PROTAC SMARCA2/4-degrader-33 (compound I-277) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4
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