| Bioactivity | EGFR-IN-123 (compound D06) is a potent EGFR inhibitor. EGFR-IN-123 inhibits PC-9G, A549, A431 and HCT116 cells with IC50s of 0.74, 1.36, 1.20 and 2.53 μM, respectively[1]. |
| CAS | 2543763-00-2 |
| Formula | C24H27F3N6O |
| Molar Mass | 472.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. FaQing Ye,et al. N4- (3-methoxyphenyl) -pyrimidinediamine targeted DDR1 inhibitor and preparation and application thereof. CN, CN111793035B. 2021-06-18. [2]. FaQing Ye,et al. N4- (3-methoxyphenyl) -pyrimidinediamine targeted DDR1 inhibitor and preparation and application thereof. CN, CN111793035B. 2021-06-18. |
EGFR-IN-123
CAS: 2543763-00-2 F: C24H27F3N6O W: 472.51
EGFR-IN-123 (compound D06) is a potent EGFR inhibitor. EGFR-IN-123 inhibits PC-9G, A549, A431 and HCT116 cells with IC50
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