| Bioactivity | PROTAC SMARCA2/4-degrader-28 (PROTAC 1) is a PROTAC-based partial degrader of SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-28 (PROTAC 1) contains a CRL2VHL ligand (S,R,S)-AHPC (HY-125845), linker (HY-159680) and a SMARCA-BD ligand (+)-JQ-1 (HY-13030)[1]. |
| CAS | 2409844-88-6 |
| Formula | C54H68ClN9O11S2 |
| Molar Mass | 1118.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Angus D Cowan, et al. Driving E3 Ligase Substrate Specificity for Targeted Protein Degradation: Lessons from Nature and the Laboratory. Annu Rev Biochem. 2022 Jun 21:91:295-319. |
PROTAC SMARCA2/4-degrader-28
CAS: 2409844-88-6 F: C54H68ClN9O11S2 W: 1118.75
PROTAC SMARCA2/4-degrader-28 (PROTAC 1) is a PROTAC-based partial degrader of SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degr
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.