| Bioactivity | PROTAC SMARCA2 degrader-22 (Compound 5) is a PROTAC degrader for SMARCA2 with a degradation efficacy of 94% at 100 nM. PROTAC SMARCA2 degrader-22 inhibits the proliferation of cell A549 with an EC50 < 250 nM[1]. |
| CAS | 2760246-90-8 |
| Formula | C44H51N9O5S |
| Molar Mass | 818.00 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. ABBINENI C, et al., 6-substituted pyridazine compounds as smarca2 and/or smarca4 degraders. WO2022029617 A1. |
PROTAC SMARCA2 degrader-22
CAS: 2760246-90-8 F: C44H51N9O5S W: 818.00
PROTAC SMARCA2 degrader-22 (Compound 5) is a PROTAC degrader for SMARCA2 with a degradation efficacy of 94% at 100 nM. P
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