| Bioactivity | PROTAC PAPD5 degrader 1 (compound 12b) inhibits both hepatitis A (HAV) and hepatitis B virus (HBV) in vitro and in vivo[1], with IC50 and CC50 of 10.59 μM and ＞ 50 μM, respectively in Huh7 cells[1]. |
| Formula | C49H63N5O16 |
| Molar Mass | 978.05 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. You Li, et al. “PROTAC” modified Dihydroquinolizinones (DHQs) that causes degradation of PAPD-5 and inhibition of hepatitis a virus and hepatitis B virus, in vitro. Bioorg Med Chem Lett. 2024 Feb 29:102:129680. |
PROTAC PAPD5 degrader 1
CAS: F: C49H63N5O16 W: 978.05
PROTAC PAPD5 degrader 1 (compound 12b) inhibits both hepatitis A (HAV) and hepatitis B virus (HBV) in vitro and in vivo,
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