Bioactivity | PROTAC HPK1 Degrader-2 (compound 3) is a PROTAC degrader of HPK1, with the DC50 of 23 nM in human PBMC. PROTAC HPK1 Degrader-2 plays an important role in cancer research[1]. |
CAS | 2893885-31-7 |
Formula | C43H47N9O4 |
Molar Mass | 753.89 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. BeiGene, Ltd. Preparation of pyrrolo[2,3-b]pyrazine-based bifunctional compounds as HPK1 degraders and the use thereof. World Intellectual Property Organization, WO2023006063 A1 2023-02-02. |