HIV gp120 (318-327)_product_DataBase

Bioactivity	HIV gp120 (318-327) is a short sequence of the HIV-1 strain IIIB envelope peptide (rgpgrafvti) that corresponds to the conserved C-terminal region of the glycoprotein. HIV gp120 (318-327) is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIV gp120 (318-327) lacks the A2 anchor residues recognized by epitope-specific CTLs but has structural features that confer promiscuous A2 binding[1][2].
Invitro	HIV gp120 (318-327) (0.5 μM) stimulats a diminished CTL response in JA2 cells expressing the 7DV3 mutant[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> HIV gp120 (318-327) 相关抗体:
CAS	147841-68-7
Sequence	Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile
Shortening	RGPGRAFVTI
Formula	C48H80N16O12
Molar Mass	1073.25
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Kmieciak D, et al. The effect of deletion of the V3 loop of gp120 on cytotoxic T cell responses and HIV gp120-mediated pathogenesis. J Immunol. 1998 Jun 1;160(11):5676-83. [2]. Gu L, et al. A recombinant adenovirus-based vector elicits a specific humoral immune response against the V3 loop of HIV-1 gp120 in mice through the "Antigen Capsid-Incorporation" strategy. Virol J. 2014 Jun 16;11:112.

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