| Bioactivity | PROTAC HDAC6 degrader 2 (Compound 1) is a HDAC6 PROTAC degrader, with IC50 of 0.643 μM. PROTAC HDAC6 degrader 2 promotes ubiquitination and degradation of HDAC6. PROTAC HDAC6 degrader 2 can be used for the research of haematological and solid cancers (Pink: HDAC6 ligand (HY-171141); Blue: E3 ligase CRBN ligand (HY-10984))[1]. |
| Formula | C34H33F2N9O8 |
| Molar Mass | 733.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Keuler T, et al. Development of the first non-hydroxamate selective HDAC6 degraders. Chem Commun (Camb). 2022 Oct 4;58(79):11087-11090. |
PROTAC HDAC6 degrader 2
CAS: F: C34H33F2N9O8 W: 733.68
PROTAC HDAC6 degrader 2 (Compound 1) is a HDAC6 PROTAC degrader, with IC50 of 0.643 μM. PROTAC HDAC6 degrader 2 promote
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