| Bioactivity | PROTAC(H-PGDS)-7 is a Hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degrader, with a DC50 of 17.3 pM[1]. |
| Invitro | PROTAC(H-PGDS)-7 shows potent suppression of prostaglandin D2 (PGD2) production in KU812 cells[1]. |
| Name | PROTAC(H-PGDS)-7 |
| CAS | 2761281-50-7 |
| Formula | C40H38N8O7 |
| Molar Mass | 742.78 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Hidetomo Yokoo, et al. Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design. J Med Chem. 2021 Nov 11;64(21):15868-15882. |