| Bioactivity | PRO-F is a photoactivable H2S donor with ROS scavenging ability. PRO-F can be activated by light to produce fluorescent signal, for real-time tracking of released H2S. PRO-F activation doesn’t consume endogenous substances. deliver H2S in an intracellular environment to protect cells from excessive reactive oxygen species (ROS) induced damage. PRO-F shows enhancement on chronic wound healing, researched in diabetic models as well[1]. |
| Invitro | PRO-F (20 μM; 0-500s) can be activated by light activation (365 nm) time-dependently, λex=530 nm, λem=676 nm[1].PRO-F (20 μM; 5 min, 10 min, 15 min) produces red fluorescent signal in NDF and HaCaT cells[1].PRO-F (20 μM; 0-500 s) 可通过时间依赖性光激活 (365 nm) 激活，λex=530 nm，λem=676 nm[1]。PRO-F (20 μM；5 分钟、10 分钟、15 分钟) 在 NDF 和 HaCaT 细胞中产生红色荧光信号[1]。 |
| Name | PRO-F |
| Formula | C34H29N3O5S |
| Molar Mass | 591.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yuan F, et al. Photoactivated Hydrogen Sulfide Donor with a Near-Infrared Fluorescence Report System for Accelerated Chronic Wound Healing. Anal Chem. 2023 May 2;95(17):6931-6939. |