| Bioactivity | PPPDA-O16B is a lipid containing disulfide bonds used for DNA delivery. PPPDA-O16B can encapsulate DNA plasmid, releasing DNA selectively via lipid degradation catalyzed by GSH[1]. |
| In Vivo | PPPDA-O16B 可以递送细菌效应蛋白 DUF5，以降解突变 RAS 并灭活下游 MAPK 信号级联，从而抑制体外和携带肿瘤的小鼠异种移植中的癌细胞生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C37H73NO4S4 |
| Molar Mass | 724.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wenting Li, et al. Intracellular delivery of bacterial effectors for cancer therapy using biodegradable lipid nanoparticles. Biomater Sci. 2023 May 2;11(9):3172-3179. |