| Bioactivity | Besifovir Dipivoxil, an analog of guanosine monophosphate, is an acyclic nucleotide phosphonate with antiviral effect. Besifovir Dipivoxil is rapidly converted by the liver and intestine to the intermediate metabolite LB80331 via the esterification process, subsequently phosphorylated into the di- and triphosphate forms, which act as antiviral DNA synthesis inhibitors. Besifovir Dipivoxil is promising for research of chronic hepatitis B[1]. |
| CAS | 441785-26-8 |
| Formula | C22H34N5O8P |
| Molar Mass | 527.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hwang JG, et al. Influence of Renal Function on the Single-Dose Pharmacokinetics of Besifovir, a Novel Antiviral Agent for theTreatment of Hepatitis B Virus Infection. J Clin Pharmacol. 2022 Jan;62(1):46-54. |
Besifovir Dipivoxil
CAS: 441785-26-8 F: C22H34N5O8P W: 527.51
Besifovir Dipivoxil, an analog of guanosine monophosphate, is an acyclic nucleotide phosphonate with antiviral effect. B
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