| Bioactivity | POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration research[1][2] | ||||||
| Invitro | A derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide that exhibits binding activity to C3, preventing cleavage to its active fragments C3a and C3b[2]. | ||||||
| Name | POT-4 | ||||||
| CAS | 934461-40-2 | ||||||
| Shortening | Ac-ICV{Trp(Me)}QDWGAHRCT-NH2 (Disulfide bridge:Cys2-Cys12) | ||||||
| Formula | C72H102N22O18S2 | ||||||
| Molar Mass | 1627.85 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
POT-4
CAS: 934461-40-2 F: C72H102N22O18S2 W: 1627.85
POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used
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