| Bioactivity | PM102 (HepArrest) is a heparin antagonist that can reverses the anticoagulant effect of heparin. PM102 potently binds heparin (Kd = 36 nM) in vitro[1]. |
| CAS | 1234564-95-4 |
| Sequence | Ac-Ala-Glu-Ala-Arg-Ala-Arg-Arg-Ala-Ala-Ala-Arg-Ala-Ala-Arg-Arg-Ala-Lys-{Lys-(Ac-Ala-Glu-Ala-Arg-Ala-Arg-Arg-Ala-Ala-Ala-Arg-Ala-Ala-Arg-Arg-Ala)}-Pro-{Dpr-(Ac-Ala-Glu-Ala-Arg-Ala-Arg-Arg-Ala-Ala-Ala-Arg-Ala-Ala-Arg-Arg-Ala)}-Glu-NH2 |
| Shortening | Ac-AEARARRAAARAARRAK-{K-(Ac-AEARARRAAARAARRA)}-P-{Dpr-(Ac-AEARARRAAARAARRA)}-E-NH2 |
| Formula | C235H425N111O64 |
| Molar Mass | 5829.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Daniel J Cushing, et al. Reversal of heparin-induced increases in aPTT in the rat by PM102, a novel heparin antagonist. Eur J Pharmacol. 2010, 635, 1-3. |
PM102
CAS: 1234564-95-4 F: C235H425N111O64 W: 5829.59
PM102 (HepArrest) is a heparin antagonist that can reverses the anticoagulant effect of heparin. PM102 potently binds he
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