| Bioactivity | PKCδ substrate acts as a nuclear transporter of ERK2 and is involved in ERK2 mediated gene activation. PKCδ is involved in the regulation of cell growth, proliferation, cell cycle arrest, and apoptosis by phosphorylating hBVR and other proteins. PKCδ substrate can be used to study the development of diseases, especially cancer biology[1]. |
| CAS | 915155-20-3 |
| Sequence | Ala-Arg-Arg-Lys-Arg-Lys-Gly-Ser-Phe-Phe-Tyr-Gly-Gly |
| Shortening | ARRKRKGSFFYGG |
| Formula | C69H108N24O16 |
| Molar Mass | 1529.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gibbs P E M, et al. Formation of ternary complex of human biliverdin reductase-protein kinase Cδ-ERK2 protein is essential for ERK2-mediated activation of Elk1 protein, nuclear factor-κB, and inducible nitric-oxidase synthase (iNOS)[J]. Journal of Biological Chemistry, 2012, 287(2): 1066-1079. |
PKCδ substrate
CAS: 915155-20-3 F: C69H108N24O16 W: 1529.75
PKCδ substrate acts as a nuclear transporter of ERK2 and is involved in ERK2 mediated gene activation. PKCδ is involve
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