| Bioactivity | PI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM[1]. |
| Name | PI3Kγ inhibitor 2 |
| CAS | 1315538-79-4 |
| Formula | C20H18F3N5O3 |
| Molar Mass | 433.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Come JH, et al. Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS). J Med Chem. 2018 Jun 28;61(12):5245 |
PI3Kγ inhibitor 2
CAS: 1315538-79-4 F: C20H18F3N5O3 W: 433.38
PI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki
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