| Bioactivity | PI3K/mTOR Inhibitor-13 is an orally active dual inhibitor of phosphoinositol 3-kinase (PI3K) and mTOR kinase. PI3K/mTOR Inhibitor-13 has potential applications in sexual diseases, solid tumor and idiopathic pulmonary fibrosis (IPF)[1][2]. |
| Invitro | PI3K/mTOR Inhibitor-13 (Compound A) (0-2 µM；48 h) 以剂量依赖性方式抑制 HFL1 细胞的增值[1]。 Cell Proliferation Assay[1] Cell Line: |
| In Vivo | PI3K/mTOR Inhibitor-13 的药代动力学 (PK) 参数[2]Species |
| Name | PI3K/mTOR Inhibitor-13 |
| CAS | 1621718-37-3 |
| Formula | C20H13F2N5O3S |
| Molar Mass | 441.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cao S, et al. Pharmaceutical combination or pharmaceutical composition for treatment of fibrotic diseases. World Intellectual Property Organization. WO2020078445. [2]. Xi N, et al. Aromatic heterocyclic compounds, pharmaceutical composition containing compounds and application of pharmaceutical composition.China.CN103965199. |
PI3K/mTOR Inhibitor-13
CAS: 1621718-37-3 F: C20H13F2N5O3S W: 441.41
PI3K/mTOR Inhibitor-13 is an orally active dual inhibitor of phosphoinositol 3-kinase (PI3K) and mTOR kinase. PI3K/mTOR
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