PI3K/mTOR Inhibitor-13 sodium_product_DataBase

Bioactivity	PI3K/mTOR Inhibitor-13 sodium is an orally active dual inhibitor of phosphoinositol 3-kinase (PI3K) and mTOR kinase. PI3K/mTOR Inhibitor-13 sodium has potential applications in sexual diseases, solid tumor and idiopathic pulmonary fibrosis (IPF)[1][2].
Invitro	PI3K/mTOR Inhibitor-13 sodium (Compound A) (0-2 µM；48 h) 以剂量依赖性方式抑制 HFL1 细胞的增值[1]。 Cell Proliferation Assay[1] Cell Line:
In Vivo	PI3K/mTOR Inhibitor-13 sodium 的药代动力学 (PK) 参数[2]Species
Name	PI3K/mTOR Inhibitor-13 sodium
CAS	2361009-23-4
Formula	C20H13F2N5NaO3S
Molar Mass	464.40
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Cao S, et al. Pharmaceutical combination or pharmaceutical composition for treatment of fibrotic diseases. World Intellectual Property Organization. WO2020078445. [2]. Xi N, et al. Aromatic heterocyclic compounds, pharmaceutical composition containing compounds and application of pharmaceutical composition.China.CN103965199.

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