| Bioactivity | PHD2-IN-2 (Compound 12) is a PHD2 inhibitor, with an IC50 of 34.3 nM. PHD2-IN-2 has high erythropoietin (EPO) inducing activity, with an EC50 of 6.79 μM. PHD2-IN-2 can be used for the research of anemia, ischemia, and hypoxia[1]. |
| In Vivo | PHD2-IN-2 (3 mg/kg，每天一次，持续 14 天) 可提高 SD 大鼠的 EPO 水平[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C19H18N4O4 |
| Molar Mass | 366.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tang HT, et al. Prolyl hydroxylase inhibitor and use thereof. WO2024061172A1. |