| Bioactivity | PHD-IN-1 (compound 80) is a potent inhibitor of PHD2，with an IC50 value of ≤5 nM. PHD-IN-1 shows EC50s of 2.5 μM in EPO Elisa assay both in Caco2-HIFla-HiBiT-clone-1 cells and Hep3B cells，respectively[1]. |
| Target | IC50: ≤5 nM (PHD2) |
| Name | PHD-IN-1 |
| CAS | 2924182-31-8 |
| Formula | C24H23N7O2 |
| Molar Mass | 441.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ding X, et al. 1,7-Naphthyridine derivatives as PHD inhibitors and their preparation. World Intellectual Property Organization, WO2023072246 A1. 2023-05-04. |