| Bioactivity | TRAF6 peptide TFA is a specific TRAF6-p62 inhibitor. TRAF6 peptide TFA potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide TFA has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1]. | ||||||
| Name | TRAF6 peptide TFA | ||||||
| Sequence | Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Glu-Ser-Ala-Ser-Gly-Pro-Ser-Glu-Asp-Pro-Ser-Val-Asn-Phe-Leu-Lys | ||||||
| Shortening | AAVALLPAVLLALLAPESASGPSEDPSVNFLK | ||||||
| Formula | C145H238N34O44.xC2HF3O2 | ||||||
| Molar Mass | 3161.64 (free acid) | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
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| Reference | [1]. Wooten, Marie W. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Patent WO2005050170A2. |
TRAF6 peptide TFA
CAS: F: C145H238N34O44.xC2HF3O2 W: 3161.64 (free acid)
TRAF6 peptide TFA is a specific TRAF6-p62 inhibitor. TRAF6 peptide TFA potently abrogates NGF-dependent TrkA ubiquitinat
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