| Bioactivity | PG-11047 (CGC-11047) is a polyamine analogue. PG-11047 can be used for the research of breast cancer[1]. |
| Invitro | PG-11047 (13 nM-5 mM; 72 h) 抑制乳腺细胞系成员的生长，范围很广，基底样细胞系在低于管腔细胞系的浓度下受到抑制[ 1].PG-11047 (0.3, 10, 300 μM; 48 h, 72 h) 在几乎不产生细胞凋亡的剂量下显示 S 期分数显着降低[1]。 Cell Cycle Analysis[1] Cell Line: |
| Name | PG-11047 |
| CAS | 308145-19-9 |
| Formula | C14H32N4 |
| Molar Mass | 256.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wen-Lin Kuo, et al. A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med. 2009 Dec 14;7:77. |