| Bioactivity | PF-4878691 (3M-852A) is a potent, orally active, and selective Toll-like receptor 7 (TLR7) agonist modelled to dissociate its antiviral and inflammatory activities[1][2]. | ||||||||||||
| Target | TLR7 | ||||||||||||
| Name | PF-4878691 | ||||||||||||
| CAS | 532959-63-0 | ||||||||||||
| Formula | C17H23N5O2S | ||||||||||||
| Molar Mass | 361.46 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Fidock MD, et al. The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691). Clin Pharmacol Ther. 2011 Jun;89(6):821-9. [2]. Horscroft NJ, et al. Antiviral applications of Toll-like receptor agonists. J Antimicrob Chemother. 2012 Apr;67(4):789-801. |
PF-4878691
CAS: 532959-63-0 F: C17H23N5O2S W: 361.46
PF-4878691 (3M-852A) is a potent, orally active, and selective Toll-like receptor 7 (TLR7) agonist modelled to dissociat
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