| Bioactivity | Dilmapimod (SB-681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. | ||||||||||||
| Invitro | Dilmapimod (SB-681323) potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression[1]. | ||||||||||||
| Name | Dilmapimod | ||||||||||||
| CAS | 444606-18-2 | ||||||||||||
| Formula | C23H19F3N4O3 | ||||||||||||
| Molar Mass | 456.42 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100. |
Dilmapimod
CAS: 444606-18-2 F: C23H19F3N4O3 W: 456.42
Dilmapimod (SB-681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pu
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