| Bioactivity | PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM[1]. |
| Target | IC50: 3 nM (MAGL) |
| Invitro | PF-06795071 shows excellent selectivity against FAAH with an IC50 of 3.1 μM[1]. |
| Name | PF-06795071 |
| CAS | 2075629-81-9 |
| Formula | C18H17F4N3O3 |
| Molar Mass | 399.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. McAllister LA, et al. Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. J Med Chem. 2018 Apr 12;61(7):3008-3026. |