| Bioactivity | PF-03382792 is a potent 5-HT4 partial agonist with a Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d. PF-03382792 can penetrate the brain. PF-03382792 produces moderate increases in cortical Ach in the rat prefrontal cortex[1]. |
| CAS | 1400811-63-3 |
| Formula | C23H32FN3O4 |
| Molar Mass | 433.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Michael A Brodney, et al.Identification of multiple 5-HT₄ partial agonist clinical candidates for the treatment of Alzheimer's disease. J Med Chem. 2012 Nov 8;55(21):9240-54. |
PF-03382792
CAS: 1400811-63-3 F: C23H32FN3O4 W: 433.52
PF-03382792 is a potent 5-HT4 partial agonist with a Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d. PF-03382792 can pene
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