| Bioactivity | PEG40K unconjugated/naked AX102 sodium is a DNA oligonucleotide aptamer for platelet-derived growth factor PDGF-B. PEG40K unconjugated/naked AX102 sodium is AX102 without PEG40K conjugation. AX102 is 34 bases in length, selectively binds platelet-derived growth factor B (PDGF-B), and causes tumor vessel regression[1]. |
| Target | PDGF-B |
| Name | PEG40K unconjugated/naked AX102 sodium |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sennino B, Falcón BL, McCauley D, Le T, McCauley T, Kurz JC, Haskell A, Epstein DM, McDonald DM. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res. 2007 Aug 1;67(15):7358-67. |