| Bioactivity | PDE8B-IN-1 hydrochloride (compound 42) is a potent, selective PDE8B inhibitor with a IC50 value of 1.5 nM. PDE8B-IN-1 hydrochloride can be used in the study of diabetes[1]. |
| Name | PDE8B-IN-1 hydrochloride |
| CAS | 1305116-67-9 |
| Formula | C14H19ClN8OS |
| Molar Mass | 382.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. DeNinno MP, et al. Discovery of triazolopyrimidine-based PDE8B inhibitors: exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetes. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5721-6. |
PDE8B-IN-1 hydrochloride
CAS: 1305116-67-9 F: C14H19ClN8OS W: 382.87
PDE8B-IN-1 hydrochloride (compound 42) is a potent, selective PDE8B inhibitor with a IC50 value of 1.5 nM. PDE8B-IN-1 hy
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