| Bioactivity | DD-03-171 is a BTK, IKFZ1 and IKFZ3 degrader, the BTK IC50 a value of 5.1 nM. DD-03-171 has an antiproliferative effect on mantle cell lymphoma (MCL) cells[1]. |
| Target | IKFC |
| Name | DD-03-171 |
| CAS | 2366132-45-6 |
| Formula | C55H62N10O8 |
| Molar Mass | 991.14 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dobrovolsky D, et al. Bruton tyrosine kinase degradation as a therapeutic strategy for cancer. Blood. 2019 Feb 28;133(9):952-961. |
DD-03-171
CAS: 2366132-45-6 F: C55H62N10O8 W: 991.14
DD-03-171 is a BTK, IKFZ1 and IKFZ3 degrader, the BTK IC50 a value of 5.1 nM. DD-03-171 has an antiproliferative effect
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