| Bioactivity | PDD00017238 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with EC50 values of 40 nM and 55 nM in biochemical assay and cell POM, respectively[1]. | ||||||||||||
| Name | PDD00017238 | ||||||||||||
| CAS | 1952247-05-0 | ||||||||||||
| Formula | C19H20N6O3S3 | ||||||||||||
| Molar Mass | 476.60 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Dominic I James, et al. First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190. |
PDD00017238
CAS: 1952247-05-0 F: C19H20N6O3S3 W: 476.60
PDD00017238 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with EC50 values of 40 nM and 55 nM in bioc
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