PeptideDB

N6-Ethyladenosine

CAS: 14357-08-5 F: C12H17N5O4 W: 295.29

N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR
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Bioactivity N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1].
Target Ki: 4.9 nM (hA1AR), 4.7 nM (hA3AR)
Invitro N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA1AR and hA3AR over hA2AR (Ki, 8900±770 nM)[1].
Name N6-Ethyladenosine
CAS 14357-08-5
Formula C12H17N5O4
Molar Mass 295.29
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Kimand SK, et al. Three-dimensional quantitative structure-activity relationship of nucleosides acting at the A3 adenosine receptor: analysis of binding and relative efficacy. J Chem Inf Model. 2007 May-Jun;47(3):1225-33. Epub 2007 Mar 6.