PeptideDB

PD-1/PD-L1-IN-31

CAS: F: C24H24ClFN2O3 W: 442.91

PD-1/PD-L1-IN-31 is a PD-1/PD-L1 inhibitor (IC50=2.2 nM). PD-1/PD-L1-IN-31 promotes secretion of the IFN-γ, and induces
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Bioactivity PD-1/PD-L1-IN-31 is a PD-1/PD-L1 inhibitor (IC50=2.2 nM). PD-1/PD-L1-IN-31 promotes secretion of the IFN-γ, and induces immune activity of peripheral blood mononuclear cells (PBMCs) to inhibits tumor cells[1].
Name PD-1/PD-L1-IN-31
Formula C24H24ClFN2O3
Molar Mass 442.91
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Cai S, et al. Design, synthesis, and evaluation of PD-1/PD-L1 small-molecule inhibitors bearing a rigid indane scaffold. Eur J Med Chem. 2023 Aug 5;256:115468.