| Bioactivity | LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model[1]. | ||||||||||||
| Name | LNP Lipid-8 | ||||||||||||
| CAS | 2408140-60-1 | ||||||||||||
| Formula | C42H71NO7 | ||||||||||||
| Molar Mass | 702.02 | ||||||||||||
| Appearance | Oil | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Lokugamage MP, et al. Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands. Adv Mater. 2019 Oct;31(41):e1902251. |
LNP Lipid-8
CAS: 2408140-60-1 F: C42H71NO7 W: 702.02
LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells
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