PeptideDB

PCSK9-IN-23

CAS: 2115700-96-2 F: C22H18F6N2O W: 440.38

PCSK9-IN-23 (compound 5C) is a potent PCSK9 inhibitor. PCSK9-IN-23 blocks PCSK9 secretion from HepG2 cells, significantl
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Bioactivity PCSK9-IN-23 (compound 5C) is a potent PCSK9 inhibitor. PCSK9-IN-23 blocks PCSK9 secretion from HepG2 cells, significantly increases LDL receptor (LDLR) expression[1].
Name PCSK9-IN-23
CAS 2115700-96-2
Formula C22H18F6N2O
Molar Mass 440.38
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Lisa Giannessi, et al. Identification of 4-amino-2-Pyridones as new potent PCSK9 inhibitors: From phenotypic hit discovery to in vivo tolerability. Eur J Med Chem. 2023 Dec 20:265:116063.