| Bioactivity | PC58538 is a cell division inhibitor, targeting to FtsZ. PC58538 shows moderate antibacterial activity, and inhibits cell division in vegetative cells of wild-type B. subtilis. PC58538 is also known to modulate the rate of GTP hydrolysis[1][2]. |
| Invitro | PC58538 (128 g/mL；2 小时) 抑制细胞分裂，并使平均细胞长度增加约 5 倍[1]。 |
| Name | PC58538 |
| CAS | 434910-94-8 |
| Formula | C24H25NO3 |
| Molar Mass | 375.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Stokes NR, et al. Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay. J Biol Chem. 2005 Dec 2;280(48):39709-15. |