PeptideDB

PB94

CAS: F: C29H33N3O4 W: 487.59

PB94 is a selective HDAC11 inhibitor (IC50=108 nM). PB94 can be radiolabeled as -PB94 for use in positron emission tomog
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity PB94 is a selective HDAC11 inhibitor (IC50=108 nM). PB94 can be radiolabeled as [11C]-PB94 for use in positron emission tomography (PET), as well as brain uptake and metabolic properties in administered live animals. PB94 improves neuropathic pain in mice and could be used to study neurological indications[1].
Target IC50: 108 nM (HDAC11)
Name PB94
Formula C29H33N3O4
Molar Mass 487.59
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Bai P et al. Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice. J Med Chem. 2023 Nov 16.