Bioactivity | Parp7-in-18 (Compund 8) is a selective PARP7 inhibitor with an IC50 of 0.11 nM. PARP7-IN-18 exhibits good anticancer activity and pharmacokinetic properties[1]. |
Name | PARP7-IN-18 |
CAS | 2819999-00-1 |
Formula | C23H26ClF3N6O4 |
Molar Mass | 542.94 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xu J, et al. Discovery of tricyclic PARP7 inhibitors with high potency, selectivity, and oral bioavailability[J]. European Journal of Medicinal Chemistry, 2024: 116160. |