| Bioactivity | 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a Kd value ≤ 7 nM. 1400W has relatively weaker inhibition on human neuronal NOS and endothelial NOS (eNOS), with Ki values of 2 μM and 50 μM, respectively[1]. |
| Name | 1400W |
| CAS | 180001-34-7 |
| Formula | C10H15N3 |
| Molar Mass | 177.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Garvey EP, et al. 1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo. J Biol Chem. 1997 Feb 21;272(8):4959-63. |