PAR 4 (1-6) (human)_product_DataBase

Bioactivity	PAR 4 (1-6) human, a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist[1].
Invitro	PAR 4 (1-6) (GYPGQV) 促进平滑肌细胞 (SMC) 中的[3H]-胸腺嘧啶掺入。在500 μM浓度时，该肽将DNA合成提高到对照的2.5倍。与分别用10 nM 的凝血酶或100 μM的SFLLRN刺激SMC所得到的类似的促增殖效果相当。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PAR 4 (1-6) (human) 相关抗体:
CAS	225779-44-2
Sequence	Gly-Tyr-Pro-Gly-Gln-Val
Shortening	GYPGQV
Formula	C28H41N7O9
Molar Mass	619.67
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. H Andersen, et al. Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11189-93. [2]. E Bretschneider, et al. Evidence for functionally active protease-activated receptor-4 (PAR-4) in human vascular smooth muscle cells. Br J Pharmacol. 2001 Apr;132(7):1441-6.

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