PAD4-IN-2_product_DataBase

CAS: 2642327-52-2 F: C20H23BClN7O6 W: 503.70

PAD4-IN-2 (compound 5i) is a PAD4 inhibitor (IC50=1.94 μM). PAD4-IN-2 inhibits tumor growth in mice by specifically inh

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	PAD4-IN-2 (compound 5i) is a PAD4 inhibitor (IC50=1.94 μM). PAD4-IN-2 inhibits tumor growth in mice by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils[1].
Target	IC50: 1.94 μM (PAD4).
Name	PAD4-IN-2
CAS	2642327-52-2
Formula	C20H23BClN7O6
Molar Mass	503.70
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Zhu D, et al. Highly-tumor-targeted PAD4 inhibitors with PBA modification inhibit tumors in vivo by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils. Eur J Med Chem. 2023 Oct 5;258:115619.

PeptideDB