| Bioactivity | Nav1.3 channel inhibitor 1 (compound 15b) is a state-dependent voltage-gated sodium channel Nav1.3 inhibitor (IC50=20 nM). Nav1.3 channel inhibitor 1 can penetrate the blood-brain barrier and can be used in the research of nervous system diseases[1]. |
| Target | IC50: 20 nM (Nav1.3). |
| Name | Nav1.3 channel inhibitor 1 |
| Formula | C19H15F2N3O3S2 |
| Molar Mass | 435.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zidar N, et al. New aryl and acylsulfonamides as state-dependent inhibitors of Nav1.3 voltage-gated sodium channel. Eur J Med Chem. 2023 Oct 5;258:115530. |
Nav1.3 channel inhibitor 1
CAS: F: C19H15F2N3O3S2 W: 435.47
Nav1.3 channel inhibitor 1 (compound 15b) is a state-dependent voltage-gated sodium channel Nav1.3 inhibitor (IC50=20 nM
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