| Bioactivity | P2X7-IN-2 TFA (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 TFA inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 TFA can be used for the research of autoimmunity, inflammation and cardiovascular disease[1]. |
| Target | IC50: 0.01 nM (human whole blood IL-Iβ release) |
| Invitro | P2X7-IN-2 TFA（0-1 μM；30 分钟）抑制人全血 IL-Iβ 释放，IC50 值为 0.01 nM[1]。 |
| Name | P2X7-IN-2 TFA |
| Formula | C24H22F7N3O4 |
| Molar Mass | 549.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kelly, Michael G, et al. Preparation of isoquinolonecarboxamides as P2X7 purinoceptor modulators and uses thereof. WO2008112205 A1. 2008. |