| Bioactivity | Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice[1][2]. |
| Name | Orphanin FQ(1-11) |
| CAS | 178249-41-7 |
| Shortening | FGGFTGARKSA |
| Formula | C49H75N15O14 |
| Molar Mass | 1098.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Reinscheid RK, et al. Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J Biol Chem. 1996;271(24):14163-14168. [2]. Rossi GC, et al. Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J Pharmacol Exp Ther. 1997;282(2):858-865. |
Orphanin FQ(1-11)
CAS: 178249-41-7 F: C49H75N15O14 W: 1098.21
Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a K
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