| Bioactivity | Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity[1]. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence[2]. | ||||||||||||
| Invitro | Oroxin A (0.5- 100 μM; 24 hours) significantly increases the PPARγ transcription level and exhibits the strongest activation with 50 μM in HEK-293t cells[1]. | ||||||||||||
| Name | Oroxin A | ||||||||||||
| CAS | 57396-78-8 | ||||||||||||
| Formula | C21H20O10 | ||||||||||||
| Molar Mass | 432.38 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
Oroxin A
CAS: 57396-78-8 F: C21H20O10 W: 432.38
Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxi
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.