| Bioactivity | Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects[1][2][3][4][5][6]. |
| Invitro | Farrerol observably reduces the production of inflammatory mediators including IL-1β, IL-6, TNF-α, COX-2, and iNOS in LPS-induced RAW264.7 cells via suppressing AKT, ERK1/2, JNK1/2, and NF-κB p65 phosphorylation[1].Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line[2].Farrerol inhibits angiogenesis through Akt/mTOR, Erk and Jak2/Stat3 signal pathway[3].Farrerol overcomes the invasiveness of lung squamous cell carcinoma cells by regulating the expression of inducers of epithelial mesenchymal transition[4].Farrerol ameliorates acetaminophen-induced hepatotoxicity via activation of Nrf2 and autophagy[6]. |
| Name | Farrerol |
| CAS | 24211-30-1 |
| Formula | C17H16O5 |
| Molar Mass | 300.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Farrerol
CAS: 24211-30-1 F: C17H16O5 W: 300.31
Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, an
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