| Bioactivity | Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities. | ||||||||||||
| Invitro | Oleanolic acid (OA) suppresses the proliferation of lung cancer cells in both dose- and time-dependent manners, along with an increase in miR-122 abundance. CCNG1 and MEF2D, two putative miR-122 targets, are found to be downregulated by OA treatment [1]. OA induces autophagy in normal tissue-derived cells without cytotoxicity. OA-induced autophagy is shown to decrease the proliferation of KRAS-transformed normal cells and to impair their invasion and anchorage-independent growth[2]. | ||||||||||||
| Name | Oleanolic Acid | ||||||||||||
| CAS | 508-02-1 | ||||||||||||
| Formula | C30H48O3 | ||||||||||||
| Molar Mass | 456.70 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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